Research
Pulsed Electromagnetic Field (P.E.M.F.) Therapy
Pulsed Electromagnetic Field Therapy (PEMF) works at a cellular level to stabilize imbalances within the body that cause pain and inflammation. By increasing the blood flow to the treated area the permeability of the cell wall increases, causing the nutrients, like oxygen and protein, to be absorbed more efficiently. Damaging toxins and cellular waste can exit the cell more efficiently through the lymphatic (detox) system. Some results include pain relief, increased mobility, reduction of inflammation, enhanced effectiveness of medication, and alleviation of discomfort due to compensation.
Real-world treatment outcomes of transcranial pulsating electromagnetic fields as augmentation therapy for treatment-resistant depression
Rikke Hedegaard Jensen, René Ernst Nielsen, Gustav Bizik,
Real-world treatment outcomes of transcranial pulsating electromagnetic fields as augmentation therapy for treatment-resistant depression,Journal of Affective Disorders,Volume 368,2025,Pages 487-492,ISSN 0165-0327
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Fiani B, Kondilis A, Runnels J, Rippe P, Davati C. Pulsed Electromagnetic Field Stimulators Efficacy for Noninvasive Bone Growth in Spine Surgery. J Korean Neurosurg Soc. 2021 Jul;64(4):486-494. doi: 10.3340/jkns.2020.0269. Epub 2021 Jun 11. PMID: 34107606; PMCID: PMC8273786.
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Ross CL, Zhou Y, McCall CE, Soker S, Criswell TL. The Use of Pulsed Electromagnetic Field to Modulate Inflammation and Improve Tissue Regeneration: A Review. Bioelectricity. 2019 Dec 1;1(4):247-259. doi: 10.1089/bioe.2019.0026. Epub 2019 Dec 12. PMID: 34471827; PMCID: PMC8370292.
"Consistent outcomes in studies involving animal and human tissue have shown promise for the use of PEMF as an alternative or complementary treatment to pharmaceutical therapies.Thus, PEMF treatment could provide a novel nonpharmaceutical means of modulating inflammation in injured tissues resulting in enhanced functional recovery. This review cites published data that support the use of PEMF to improve tissue regeneration. Our studies included herein confirm anti-inflammatory effects of PEMF on MSCs and MΦ."
Ross CL, Ang DC, Almeida-Porada G. Targeting Mesenchymal Stromal Cells/Pericytes (MSCs) With Pulsed Electromagnetic Field (PEMF) Has the Potential to Treat Rheumatoid Arthritis. Front Immunol. 2019 Mar 4;10:266. doi: 10.3389/fimmu.2019.00266. PMID: 30886614; PMCID: PMC6409305.
"PEMF is emerging as a novel and highly promising means of treating chronic inflammation and aberrant immunity that exists in diseases such as RA. It can be used to target aberrant MSCs to potentially bring the inflammatory milieu back to homeostasis. Cellular electrical properties such as membrane surface charge and membrane potential can be readily influenced by PEMF (151–153), which can affect oscillatory frequencies of the myriad of enzymes present within the cells. PEMF can also influence cell membranes, nucleic acids, and bioelectrical phenomena generated by coherent groups of cells that are essential to cell-to-cell communication processes (154, 155). PEMF appears to exert its effects on cellular function and differentiation by altering the spatial and temporal patterns of intracellular calcium (Ca2+) concentration (10) and restoring levels/activity of potassium (K+) channels (17, 156, 157). By restoring normal Ca2+ ion flux and Na+/K+ balance, the cell can begin the process of down-regulating inflammatory cytokines, heat-shock proteins, and proangiogenic molecules such as VEGF (157), making it possible for the body to commence rebuilding healthy cartilage."